Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts

Background and aims: Insulin-like growth factor (IGF) I receptor (IGF-Ir) signalling is required for carcinogenicity and proliferation of many tumours but this pathway has not been studied in detail in gastric cancer. We have previously shown successful therapy for colorectal, pancreatic, and lung c...

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Hlavní autoři: Min, Y, Adachi, Y, Yamamoto, H, Imsumran, A, Arimura, Y, Endo, T, Hinoda, Y, Lee, C-T, Nadaf, S, Carbone, D P, Imai, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2005 by Gut 2005
Témata:
Gastric Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774471/
https://ncbi.nlm.nih.gov/pubmed/15831900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.048926
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