Lung restricted T cell receptor AV2S3+ CD4+ T cell expansions in sarcoidosis patients with a shared HLA-DRß chain conformation

Background: Sarcoidosis is a systemic disease of unknown aetiology frequently affecting the lungs. CD4+ T cells, in particular, accumulate in the lungs, implicating them in the pathogenesis of the disease. Methods: T cell receptor (TCR) variable (V) gene expression on bronchoalveolar lavage (BAL) fl...

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Auteurs principaux: Grunewald, J, Wahlstrom, J, Berlin, M, Wigzell, H, Eklund, A, Olerup, O
Format: Artigo
Langue:Inglês
Publié: BMJ Group 2002
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746294/
https://ncbi.nlm.nih.gov/pubmed/11923555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.57.4.348
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