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Efficacy of statin therapy: possible effect of phenytoin

Statins are currently the most widely prescribed lipid-lowering drugs. Individual statins are known to be metabolised by the CYP3A4 isoform of the cytochrome P450 system. The effect of CYP3A4 inducers such as phenytoin on the metabolism and efficacy of these agents is unknown. We report a patient wi...

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Hlavní autoři: Murphy, M, Dominiczak, M
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1741263/
https://ncbi.nlm.nih.gov/pubmed/10435174
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