Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparum.

The major merozoite surface protein of Plasmodium falciparum (PfMSP1) is a candidate antigen for a malaria vaccine. A 19-kDa C-terminal processing product of PfMSP1 (PfMSP1(19)) is composed of two domains sharing a cysteine-rich motif with epidermal growth factor (EGF) and is the target of monoclona...

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Main Authors: Egan, A F, Chappel, J A, Burghaus, P A, Morris, J S, McBride, J S, Holder, A A, Kaslow, D C, Riley, E M
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC173017/
https://ncbi.nlm.nih.gov/pubmed/7822010
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