Selection of hepatitis B surface "escape" mutants during passive immune prophylaxis following liver transplantation: potential impact of genetic changes on polymerase protein function

CASE REPORT—A patient is described who developed hepatitis B virus (HBV) reinfection five months following liver transplantation. Failure of hepatitis B immunoglobulin prophylaxis was associated with the emergence of mutations. HBV gene sequencing identified nucleotide substitutions associated with...

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Detalhes bibliográficos
Main Authors: Shields, P, Owsianka, A, Carman, W, Boxall, E, Hubscher, S, Shaw, J, O'Donnell, K, Elias, E, Mutimer, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727596/
https://ncbi.nlm.nih.gov/pubmed/10403747
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