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Activities of beta-lactam antibiotics against Escherichia coli strains producing extended-spectrum beta-lactamases.
Seven extended-spectrum beta-lactamases related to TEM and four enzymes derived from SHV-1 were transferred to a common Escherichia coli host so that the activity of a variety of beta-lactams could be tested in a uniform genetic environment. For most derivatives, penicillinase activity was 10% or le...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
Published: |
1990
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC171706/ https://ncbi.nlm.nih.gov/pubmed/2193623 |
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