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Fibrin-Induced Skin Fibrosis in Mice Deficient in Tissue Plasminogen Activator

The deposition of fibrin is an integral part of the tissue repair process, but its persistence is also associated with a number of fibrotic conditions. This study addressed the hypothesis that reduced fibrinolysis and fibrin persistence are associated with an enhanced accumulation of collagen and th...

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Bibliographic Details
Main Authors: de Giorgio-Miller, Alexander, Bottoms, Steve, Laurent, Geoffrey, Carmeliet, Peter, Herrick, Sarah
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698739/
https://ncbi.nlm.nih.gov/pubmed/16127152
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