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Microneedle-Based Intradermal Delivery of the Anthrax Recombinant Protective Antigen Vaccine

The recombinant protective antigen (rPA) of Bacillus anthracis is a promising anthrax vaccine. We compared serum immunoglobulin G levels and toxin-neutralizing antibody titers in rabbits following delivery of various doses of vaccine by microneedle-based intradermal (i.d.) delivery or intramuscular...

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Detalhes bibliográficos
Main Authors: Mikszta, John A., Dekker, John P., Harvey, Noel G., Dean, Cheryl H., Brittingham, John M., Huang, Joanne, Sullivan, Vincent J., Dyas, Beverly, Roy, Chad J., Ulrich, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698069/
https://ncbi.nlm.nih.gov/pubmed/17030580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01210-06
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