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PKB and megalin determine the survival or death of renal proximal tubule cells
Renal proximal tubule cells have a remarkable ability to reabsorb large quantities of albumin through megalin-mediated endocytosis. This is an essential process for overall body homeostasis. Overstressing this endocytic system with a prolonged excess of albumin is injurious to proximal tubule cells....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693744/ https://ncbi.nlm.nih.gov/pubmed/17121993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605029103 |
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