Llwytho...

PKB and megalin determine the survival or death of renal proximal tubule cells

Renal proximal tubule cells have a remarkable ability to reabsorb large quantities of albumin through megalin-mediated endocytosis. This is an essential process for overall body homeostasis. Overstressing this endocytic system with a prolonged excess of albumin is injurious to proximal tubule cells....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Caruso-Neves, Celso, Pinheiro, Ana Acacia S., Cai, Hui, Souza-Menezes, Jackson, Guggino, William B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693744/
https://ncbi.nlm.nih.gov/pubmed/17121993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605029103
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