Characterization of an Immunodominant Antigenic Site on GB Virus C Glycoprotein E2 That Is Involved in Cell Binding

GB virus type C (GBV-C) is a human flavivirus that may cause persistent infection, although most infected individuals clear viremia and develop antibodies to the envelope glycoprotein E2. To study GBV-C E2 antigenicity and cell binding, murine anti-E2 monoclonal antibodies (MAbs) were evaluated to t...

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Main Authors: McLinden, James H., Kaufman, Thomas M., Xiang, Jinhua, Chang, Qing, Klinzman, Donna, Engel, Alfred M., Hess, Georg, Schmidt, Urban, Houghton, Michael, Stapleton, Jack T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676310/
https://ncbi.nlm.nih.gov/pubmed/17035329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01206-06
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