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Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel

Inward rectifier K(+) channels commonly exhibit long openings (slow gating) punctuated by rapid open–close transitions (fast gating), suggesting that two separate gates may control channel open–closed transitions. Previous studies have suggested possible gate locations at the selectivity filter and...

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Détails bibliographiques
Auteurs principaux: Xie, Lai-Hua, John, Scott A, Ribalet, Bernard, Weiss, James N
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665335/
https://ncbi.nlm.nih.gov/pubmed/15459242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.072330
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