Molecular basis of slow activation of the human ether-á-go-go related gene potassium channel

The human ether-á-go-go related gene (HERG) encodes the pore forming α-subunit of the rapid delayed rectifier K(+) channel which is central to the repolarization phase of the cardiac action potential. HERG K(+) channels have unusual kinetics characterized by slow activation and deactivation, yet rap...

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Autores principales: Subbiah, Rajesh N, Clarke, Catherine E, Smith, David J, Zhao, JingTing, Campbell, Terence J, Vandenberg, Jamie I
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664982/
https://ncbi.nlm.nih.gov/pubmed/15181157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.062588
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