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Renal fibrosis: not just PAI-1 in the sky

A delicate balance exists between ECM synthesis and degradation such that interruption of the corresponding pathways results in increased plasminogen activator inhibitor-1 (PAI-1), pathological matrix accumulation, and glomerulosclerosis. A new study demonstrates that therapy with a mutant PAI-1 inc...

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Bibliografske podrobnosti
Glavni avtor: Fogo, Agnes B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC166301/
https://ncbi.nlm.nih.gov/pubmed/12897200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319375
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