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Renal fibrosis: not just PAI-1 in the sky
A delicate balance exists between ECM synthesis and degradation such that interruption of the corresponding pathways results in increased plasminogen activator inhibitor-1 (PAI-1), pathological matrix accumulation, and glomerulosclerosis. A new study demonstrates that therapy with a mutant PAI-1 inc...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2003
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166301/ https://ncbi.nlm.nih.gov/pubmed/12897200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319375 |
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