Chimeric Human Papillomavirus Type 16 (HPV-16) L1 Particles Presenting the Common Neutralizing Epitope for the L2 Minor Capsid Protein of HPV-6 and HPV-16

Both the Human papillomavirus (HPV) major (L1) and minor (L2) capsid proteins have been well investigated as potential vaccine candidates. The L1 protein first oligomerizes into pentamers, and these capsomers assemble into virus-like particles (VLPs) that are highly immunogenic. Here we examine the...

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Detalles Bibliográficos
Main Authors: Varsani, Arvind, Williamson, Anna-Lise, de Villiers, Debbie, Becker, Inga, Christensen, Neil D., Rybicki, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165259/
https://ncbi.nlm.nih.gov/pubmed/12857908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8386-8393.2003
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