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An unusual type IB topoisomerase from African trypanosomes
African trypanosomes are ancient eukaryotes that cause lethal disease in humans and cattle. Available drugs are inadequate and the need for new therapeutic targets is great. Trypanosoma brucei and related pathogens differ strikingly from higher eukaryotes in many aspects of nucleic acid structure an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164622/ https://ncbi.nlm.nih.gov/pubmed/12810956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1330762100 |
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