Viral and Cellular Determinants of the Hepatitis C Virus Envelope-Heparan Sulfate Interaction

Cellular binding and entry of hepatitis C virus (HCV) are the first steps of viral infection and represent a major target for antiviral antibodies and novel therapeutic strategies. We have recently demonstrated that heparan sulfate (HS) plays a key role in the binding of HCV envelope glycoprotein E2...

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Autors principals: Barth, Heidi, Schnober, Eva K., Zhang, Fuming, Linhardt, Robert J., Depla, Erik, Boson, Bertrand, Cosset, Francois-Loic, Patel, Arvind H., Blum, Hubert E., Baumert, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641783/
https://ncbi.nlm.nih.gov/pubmed/16928753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00941-06
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