Evidence for Transcriptional and Posttranscriptional Alterations of the Sodium/Iodide Symporter Expression in Hypofunctioning Benign and Malignant Thyroid Tumors

The uptake of iodide by epithelial thyroid cells requires the expression of a specific transporter, the Na(+)/I(−) symporter, NIS. Benign and malignant thyroid tumors of epithelial origin show a decrease up to a loss of iodide uptake activity. Previous studies of the human NIS (hNIS) gene expression...

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Autors principals: Trouttet-Masson, Séverine, Selmi-Ruby, Samia, Bernier-Valentin, Françoise, Porra, Valérie, Berger-Dutrieux, Nicole, Decaussin, Myriam, Peix, Jean-Louis, Perrin, Agnès, Bournaud, Claire, Orgiazzi, Jacques, Borson-Chazot, Françoise, Franc, Brigitte, Rousset, Bernard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2004
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618532/
https://ncbi.nlm.nih.gov/pubmed/15215159
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