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A nonpetide integrin antagonist can inhibit epithelial cell ingestion of Streptococcus pyogenes by blocking formation of integrin α5β1-fibronectin-M1 protein complexes

Streptococcus pyogenes can be efficiently internalized by a variety of human epithelial cells. β-lactam antibiotics, commonly used to treat S. pyogenes infections, do not readily permeate mammalian cells. There is growing evidence that the ability of streptococci to enter host cells contributes to t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cue, David, Southern, Sarka O., Southern, Peter J., Prabhakar, Jadhar, Lorelli, William, Smallheer, Joanne M., Mousa, Shaker A., Cleary, P. Patrick
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC16020/
https://ncbi.nlm.nih.gov/pubmed/10706638
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