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A nonpetide integrin antagonist can inhibit epithelial cell ingestion of Streptococcus pyogenes by blocking formation of integrin α5β1-fibronectin-M1 protein complexes

Streptococcus pyogenes can be efficiently internalized by a variety of human epithelial cells. β-lactam antibiotics, commonly used to treat S. pyogenes infections, do not readily permeate mammalian cells. There is growing evidence that the ability of streptococci to enter host cells contributes to t...

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Bibliografiset tiedot
Päätekijät: Cue, David, Southern, Sarka O., Southern, Peter J., Prabhakar, Jadhar, Lorelli, William, Smallheer, Joanne M., Mousa, Shaker A., Cleary, P. Patrick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC16020/
https://ncbi.nlm.nih.gov/pubmed/10706638
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