A nonpetide integrin antagonist can inhibit epithelial cell ingestion of Streptococcus pyogenes by blocking formation of integrin α5β1-fibronectin-M1 protein complexes

Streptococcus pyogenes can be efficiently internalized by a variety of human epithelial cells. β-lactam antibiotics, commonly used to treat S. pyogenes infections, do not readily permeate mammalian cells. There is growing evidence that the ability of streptococci to enter host cells contributes to t...

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Xehetasun bibliografikoak
Egile Nagusiak: Cue, David, Southern, Sarka O., Southern, Peter J., Prabhakar, Jadhar, Lorelli, William, Smallheer, Joanne M., Mousa, Shaker A., Cleary, P. Patrick
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC16020/
https://ncbi.nlm.nih.gov/pubmed/10706638
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