Nitrosylcobalamin Promotes Cell Death via S Nitrosylation of Apo2L/TRAIL Receptor DR4

We have previously demonstrated that nitrosylcobalamin (NO-Cbl), an analogue of vitamin B(12) that delivers nitric oxide (NO), had potent antiproliferative activity against several human cancer cell lines. NO-Cbl induced apoptosis via a death receptor/caspase-8 pathway. In this study, we demonstrate...

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Detaylı Bibliyografya
Asıl Yazarlar: Tang, Zhuo, Bauer, Joseph A., Morrison, Bei, Lindner, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592761/
https://ncbi.nlm.nih.gov/pubmed/16847314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00199-06
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