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Nitrosylcobalamin Promotes Cell Death via S Nitrosylation of Apo2L/TRAIL Receptor DR4
We have previously demonstrated that nitrosylcobalamin (NO-Cbl), an analogue of vitamin B(12) that delivers nitric oxide (NO), had potent antiproliferative activity against several human cancer cell lines. NO-Cbl induced apoptosis via a death receptor/caspase-8 pathway. In this study, we demonstrate...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592761/ https://ncbi.nlm.nih.gov/pubmed/16847314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00199-06 |
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