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Sildenafil (Viagra) reduces arrhythmia severity during ischaemia 24 h after oral administration in dogs
Sildenafil (Viagra) prolongs repolarisation in cardiac muscle, an effect that could lead to ventricular fibrillation (VF). Sildenafil (2 mg kg(−1)) was given by mouth to 12 mongrel dogs and, 24 h later, these dogs were anaesthetised, thoracotomised and subjected to a 25 min occlusion of the anterior...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574240/ https://ncbi.nlm.nih.gov/pubmed/14744808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705658 |
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