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Bradykinin potentiation by ACE inhibitors: a matter of metabolism

1. Studies in isolated cells overexpressing ACE and bradykinin type 2 (B(2)) receptors suggest that ACE inhibitors potentiate bradykinin by inhibiting B(2) receptor desensitization, via a mechanism involving protein kinase C (PKC) and phosphatases. Here we investigated, in intact porcine coronary ar...

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Bibliographic Details
Main Authors: Tom, Beril, Dendorfer, Andreas, Vries, René de, Saxena, Pramod R, Jan Danser, A H
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573486/
https://ncbi.nlm.nih.gov/pubmed/12208785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704862
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