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Role of opioid receptors in neurogenic dural vasodilation and sensitization of trigeminal neurones in anaesthetized rats

1. Migraine headache is thought to be caused by a distension of meningeal blood vessels, the activation of trigeminal sensory neurones and the the development of a central sensitization within the trigeminal nucleus caudalis (TNC). It has been proposed that clinically effective 5-HT(1B/1D) agonists...

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Autori principali: Williamson, D J, Shepheard, S L, Cook, D A, Hargreaves, R J, Hill, R G, Cumberbatch, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572844/
https://ncbi.nlm.nih.gov/pubmed/11454653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704136
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