Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression

BACKGROUND: Transcutaneous in vivo electroporation is expected to be an effective gene-transfer method for promoting bone regeneration using the BMP-2 plasmid vector. To promote enhanced osteoinduction using this method, we simultaneously transferred cDNAs for BMP-2 and BMP-7, as inserts in the non-...

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Main Authors: Kawai, Mariko, Bessho, Kazuhisa, Maruyama, Hiroki, Miyazaki, Jun-ichi, Yamamoto, Toshio
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557501/
https://ncbi.nlm.nih.gov/pubmed/16887039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-7-62
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