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Inhibition of mouse natural killer activity by cyclosporin A.

Cyclosporin A(CSA), administered in vivo or in vitro, inhibited the spontaneous cytotoxicity of C57BL/6 and NZB/WF1 mouse spleen cells against YAC and K562 target cells in a 4 hr 51Cr release assay. Inhibition of natural killing (NK) by CSA occurred rapidly, was dose-dependent, and did not require t...

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Detalles Bibliográficos
Main Authors: Yanagihara, R H, Adler, W H
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555291/
https://ncbi.nlm.nih.gov/pubmed/6460686
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