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DNA damage is a novel response to sublytic complement C5b-9–induced injury in podocytes

In response to Ab-complement–mediated injury, podocytes can undergo lysis, apoptosis, or, when exposed to sublytic (<5% lysis) amounts of C5b-9, become activated. Following the insertion of sublytic quantities of C5b-9, there is an increase in signaling pathways and growth factor synthesis and re...

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Hlavní autoři: Pippin, Jeffrey W., Durvasula, Raghu, Petermann, Arndt, Hiromura, Keiju, Couser, William G., Shankland, Stuart J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC153762/
https://ncbi.nlm.nih.gov/pubmed/12639994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315645
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