Influence of FK506 and cyclosporin A on alloantibody production and lymphocyte activation following blood transfusion.

The effect of administration of cyclosporin A (CyA) or the novel macrolide FK506 was investigated in AO rats given DA blood transfusions. CyA (10 mg/kg, orally) or FK506 (1 mg/kg, intramuscularly) administered for 14 days from the time of transfusion effectively inhibited primary anti-MHC class I al...

Full description

Saved in:
Bibliographic Details
Main Authors: Woo, J, Propper, D J, Macleod, A M, Thomson, A W
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535490/
https://ncbi.nlm.nih.gov/pubmed/1702375
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items