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Targeted expression of a human pituitary tumor–derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

It is estimated that up to one in five individuals develop pituitary gland tumors. Despite the common occurrence of these tumors, the pathogenetic mechanisms underlying their development remain largely unknown. We report the identification of a novel pituitary tumor–derived, N-terminally truncated i...

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Hlavní autoři: Ezzat, Shereen, Zheng, Lei, Zhu, Xian-Feng, Wu, Gillian E., Asa, Sylvia L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150823/
https://ncbi.nlm.nih.gov/pubmed/11781352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14036
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