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Crucial role of CA cleavage sites in the cap-snatching mechanism for initiating viral mRNA synthesis
In viral cap-snatching, the endonuclease intrinsic to the viral polymerase cleaves cellular capped RNAs to generate capped fragments that are primers for viral mRNA synthesis. Here we demonstrate that the influenza viral polymerase, which is assembled in human cells using recombinant proteins, effec...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150342/ https://ncbi.nlm.nih.gov/pubmed/12606583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg109 |
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