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Crucial role of CA cleavage sites in the cap-snatching mechanism for initiating viral mRNA synthesis

In viral cap-snatching, the endonuclease intrinsic to the viral polymerase cleaves cellular capped RNAs to generate capped fragments that are primers for viral mRNA synthesis. Here we demonstrate that the influenza viral polymerase, which is assembled in human cells using recombinant proteins, effec...

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Sonraí Bibleagrafaíochta
Main Authors: Rao, Ping, Yuan, Weiming, Krug, Robert M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC150342/
https://ncbi.nlm.nih.gov/pubmed/12606583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg109
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