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Crucial role of CA cleavage sites in the cap-snatching mechanism for initiating viral mRNA synthesis
In viral cap-snatching, the endonuclease intrinsic to the viral polymerase cleaves cellular capped RNAs to generate capped fragments that are primers for viral mRNA synthesis. Here we demonstrate that the influenza viral polymerase, which is assembled in human cells using recombinant proteins, effec...
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Κύριοι συγγραφείς: | , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Oxford University Press
2003
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150342/ https://ncbi.nlm.nih.gov/pubmed/12606583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg109 |
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