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Induction of Apoptosis in Tumor-Associated Endothelial Cells and Therapy of Orthotopic Human Pancreatic Carcinoma in Nude Mice

Although gemcitabine has been accepted as the first-line chemotherapeutic reagent for advanced pancreatic cancer, improvement of response rate and survival is not sufficient and patients often develop resistance. We hypothesized that the inhibition of phosphorylation of epidermal growth factor recep...

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Bibliographic Details
Main Authors: Yokoi, Kenji, Kim, Sun-Jin, Thaker, Premal, Yazici, Sertac, Nam, Do-Hyun, He, Junqin, Sasaki, Takamitsu, Chiao, Paul J, Sclabas, Guido M, Abbruzzese, James L, Hamilton, Stanley R, Fidler, Isaiah J
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501424/
https://ncbi.nlm.nih.gov/pubmed/16026649
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