The hTERT and hTERC Telomerase Gene Promoters Are Activated by the Second Exon of the Adenoviral Protein, E1A, Identifying the Transcriptional Corepressor CtBP as a Potential Repressor of Both Genes

Telomerase plays a role in the unlimited replicative capacity of the majority of cancer cells and provides a potential anticancer target. The regulation of telomerase is complex but transcriptional control of its two essential components, hTERC (RNA component) and hTERT (reverse transcriptase compon...

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Detalhes bibliográficos
Main Authors: Glasspool, Rosalind M, Burns, Sharon, Hoare, Stacey F, Svensson, Catharina, Keith, W Nicol
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501281/
https://ncbi.nlm.nih.gov/pubmed/16036112
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