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Activity of LBM415 Compared to Those of 11 Other Agents against Haemophilus Species

When tested against 254 Haemophilus influenzae strains, LBM415, a peptide deformylase inhibitor, gave MIC(50) and MIC(90) values of 2.0 μg/ml and 8.0 μg/ml, respectively. The MICs were independent of β-lactam or quinolone susceptibility and the presence or absence of macrolide efflux or ribosomal pr...

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Autors principals: Bogdanovich, Tatiana, Smith, Kathy A., Clark, Catherine, Pankuch, Glenn A., Lin, Gengrong, McGhee, Pamela, Dewasse, Bonifacio, Appelbaum, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489757/
https://ncbi.nlm.nih.gov/pubmed/16801408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00106-06
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