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Direct application of plasmid DNA containing type I interferon transgenes to vaginal mucosa inhibits HSV-2 mediated mortality

The application of naked DNA containing type I interferon (IFN) transgenes is a promising potential therapeutic approach for controlling chronic viral infections. Herein, we detail the application of this approach that has been extensively used to restrain ocular HSV-1 infection, for antagonizing va...

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Detalhes bibliográficos
Main Authors: Austin, Bobbie Ann, James, Cassandra M., Härle, Peter, Carr, Daniel J.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Biological Procedures Online 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489265/
https://ncbi.nlm.nih.gov/pubmed/16900260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1251/bpo118
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