Oxidative damage of DNA by chromium(V) complexes: relative importance of base versus sugar oxidation.

Chromium(V)-mediated oxidative damage of deoxy-ribonucleic acids was investigated at neutral pH in aqueous solution by utilizing bis(2-ethyl-2-hydroxy-butanato)oxochromate(V) (I) and bis(hydroxyethyl)-amino-tris(hydroxymethyl)methane)oxochromate(V) (II). Single-stranded and double-stranded (ds) calf...

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Detalhes bibliográficos
Main Authors: Bose, R N, Moghaddas, S, Mazzer, P A, Dudones, L P, Joudah, L, Stroup, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148443/
https://ncbi.nlm.nih.gov/pubmed/10219096
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