Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies

Inhibitory immune response to exogenously infused factor VIII (FVIII) is a major complication in the treatment of hemophilia A. Generation of such inhibitors has the potential to disrupt gene therapy for hemophilia A. We explore what we believe to be a novel approach to overcome this shortcoming. Hu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shi, Qizhen, Wilcox, David A., Fahs, Scot A., Weiler, Hartmut, Wells, Clive W., Cooley, Brian C., Desai, Drashti, Morateck, Patricia A., Gorski, Jack, Montgomery, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483176/
https://ncbi.nlm.nih.gov/pubmed/16823491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28416
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados