House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms

House dust mite allergens (HDM) cause bronchoconstriction in asthma patients and induce an inflammatory response in the lungs due to the release of cytokines, chemokines and additional mediators. The mechanism how HDM components achieve this is largely unknown. The objective of this study was to ass...

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Bibliographic Details
Main Authors: Kauffman, Henk F, Tamm, Michael, Timmerman, J André B, Borger, Peter
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475882/
https://ncbi.nlm.nih.gov/pubmed/16569217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-7961-4-5
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