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Nearest neighbor affects G:C to A:T transitions induced by alkylating agents.
The influence of local DNA sequence on the distribution of G:C to A:T transitions induced in the lacI gene of E. coli by a series of alkylating agents has been analyzed. In the case of nitrosoguanidine, two nitrosoureas and a nitrosamine, a strong preference for mutation at sites proceeded 5' b...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1987
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1474466/ https://ncbi.nlm.nih.gov/pubmed/3329097 |
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