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Identifying Functionally Important Mutations from Phenotypically Diverse Sequence Data
Here we present a simple statistical method to determine the phenotypic contribution of a single mutation from libraries of mutants with diverse phenotypes in which each mutant contains a multitude of mutations. The central premise of this method is that, given M phenotypic classes, mutations that d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472340/ https://ncbi.nlm.nih.gov/pubmed/16672519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.72.5.3696-3701.2006 |
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