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Reassessing benzene risks using internal doses and Monte-Carlo uncertainty analysis.
Human cancer risks from benzene have been estimated from epidemiological data, with supporting evidence from animal bioassay data. This article reexamines the animal-based risk assessments using physiologically based pharmacokinetic (PBPK) models of benzene metabolism in animals and humans. Internal...
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Auteur principal: | |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
1996
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1469746/ https://ncbi.nlm.nih.gov/pubmed/9118928 |
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