Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.

6-MP inhibitory effects on the MLR were reversed by AIC (46%), adenine (32%), hypoxanthine (89%), adenosine (86%) and inosine (93%). AIC, adenine, hypoxanthine and inosine had no effect on azathioprine inhibition of the MLR. Adenosine at 10 microM caused 29% reversal and had no effect at 100-400 mic...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Al-Safi, S A, Maddocks, J L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1984
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463414/
https://ncbi.nlm.nih.gov/pubmed/6232936
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