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Considerations on study designs using the extreme sibpairs methods under multilocus oligogenic models.
Several issues pertinent to study designs employing extreme sibpairs (ESP) methods to detect complex oligogenic quantitative trait loci (QTL) are investigated in the setting of genome-wide multipoint scans. We demonstrate that when stringent alpha-levels are imposed (e.g., alpha = 0.00022 as recomme...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462035/ https://ncbi.nlm.nih.gov/pubmed/11973325 |
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