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A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells

Although embryonic stem (ES) cells are capable of unlimited proliferation and pluripotent differentiation, effective preparation of neural stem cells from ES cells are not achieved. Here, we have directly generated under the coculture with dissociated primary neurosphere cells in serum-free medium a...

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Autori principali: Kato, Takeo, Heike, Toshio, Okawa, Katsuya, Haruyama, Munetada, Shiraishi, Kazuhiro, Yoshimoto, Momoko, Nagato, Masako, Shibata, Minoru, Kumada, Tomohiro, Yamanaka, Yasunari, Hattori, Haruo, Nakahata, Tatsutoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458690/
https://ncbi.nlm.nih.gov/pubmed/16595632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509789103
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