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Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of γ-Secretase activity

Cell interactions mediated by Notch family receptors have been implicated in the specification of tissue boundaries. Tightly localized activation of Notch is crucial for the formation of sharp boundaries. In the Drosophila wing imaginal disc, the Notch receptor is expressed in all cells. However, No...

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Detalhes bibliográficos
Main Authors: Herranz, Héctor, Stamataki, Evaggelia, Feiguin, Fabián, Milán, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456882/
https://ncbi.nlm.nih.gov/pubmed/16440003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400617
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