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Genetic Modifier Screens on Hairless Gain-of-Function Phenotypes Reveal Genes Involved in Cell Differentiation, Cell Growth and Apoptosis in Drosophila melanogaster

Overexpression of Hairless (H) causes a remarkable degree of tissue loss and apoptosis during imaginal development. H functions as antagonist in the Notch-signaling pathway in Drosophila, and the link to growth and apoptosis is poorly understood. To further our insight into H-mediated apoptosis, we...

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Detalhes bibliográficos
Main Authors: Müller, Dominik, Kugler, Sabrina J., Preiss, Anette, Maier, Dieter, Nagel, Anja C.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2005 by the Genetics Society of America 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456817/
https://ncbi.nlm.nih.gov/pubmed/16118195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.044453
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